Individual differences in pain
疼痛的个体差异

摘要

目的 疼痛体验的特点是个体间的巨大差异。本文回顾产生疼痛差异的文献，总结产生差异的原因。方法 回顾已发表的疼痛个体差异文献。提取疼痛个体差异变量，总结性分析产生原因，及干预策略。结果 多种生物和社会心理变量导致这些个体疼痛差异，包括人口统计学变量、遗传因素和社会心理过程。疼痛的遗传关联因性别和种族而异。而且，遗传因素还与心理社会因素相互作用，包括压力和灾难性疼痛，从而影响疼痛。这些生物和社会心理变量的个体和综合影响导致了独特的因素组合，这些因素导致了每个人的疼痛。结论 了解这些因素对于提供最佳疼痛治疗至关重要，未来的研究需要进一步阐明这些生物心理社会相互作用的性质，以便提供更明智和个性化的疼痛护理。

Abstract

Objective Pain experience is characterized by large inter-individual variability. This article reviews the literature on the differences in pain and summarizes the reasons for the differences.
Methods A review of the published literature on individual differences in pain was performed. Individual differences in pain variables were extracted, and the causes and intervention strategies were summarily analyzed.
Results Multiple biological and psychosocial variables contributed to these individual differences in pain, including demographic variables, genetic factors, and psychosocial processes. Genetic associations for pain vary by gender and ethnicity. Moreover, genetic factors also interact with psychosocial factors, including stress and catastrophic pain, to influence pain. The individual and combined effects of these biological and psychosocial variables result in a unique combination of factors that contribute to each individual's pain.
Conclusion  s Understanding these factors is critical for providing optimal pain care, and future research is needed to further elucidate the nature of these biopsychosocial interactions in order to provide more informed and personalized pain care.