摘要
目的 研究和分析慢性鼻窦炎伴鼻息肉以及单纯性慢性鼻窦炎的不同病变程度影响其并发支气管哮喘（简称哮喘）严重程度的关键因素。方法 共随机选取180名本院耳鼻喉科2019年1月至2021年3月中确诊为慢性鼻窦炎患者，完善根据症状，完善鼻内镜，鼻窦CT，肺功能检查，根据是否伴发鼻息肉，分为慢性鼻窦炎伴发鼻息肉组（共123例）和慢性鼻窦炎组（共57例），并根据肺功能检查结果，将支气管哮喘肺功能受阻塞程度分为轻度和重度，通过 Spearman相关分析比较不同病变程度和范围的慢性鼻窦炎对哮喘的影响。结果 ①鼻息肉的严重程度与慢性哮喘患者的哮喘严重程度无统计学意义（P＞0.05），②慢性鼻窦炎的鼻窦病变范围与哮喘患者哮喘严重程度成正相关（r=0.613，P＜0.05）。③当慢性鼻窦炎发生窦口鼻道复合体阻塞，无论伴发鼻息肉（r=0.408，P＜0.05）和还是单纯性鼻窦炎（r=0.492，P＜0.05）均会加重支气管哮喘患者哮喘严重程度。结论 慢性鼻窦炎的病变范围和严重程度与支气管哮喘哮喘严重程度存在一定正相关性并有待进一步深入研究。
关键词： 慢性鼻窦炎；哮喘；鼻息肉；严重程度；关键因素
Abstract
Objective To study and analyze the correlation between bronchial asthma (asthma) and chronic sinusitis with nasal polyp and simple chronic sinusitis. Methods a total of 180 randomly selected from January 2019 to 2021 in our hospital otolaryngology mid-march diagnosed with chronic sinusitis patients, improve according to the symptoms, improve the sinus CT, pulmonary function testing, according to the results of the CT scan is divided into chronic sinusitis with nasal polyp group (123 cases) and chronic sinusitis (57 cases), lung function and according to the test results, The degree of lung function obstruction in bronchial asthma was divided into mild and severe. The influence of different degree and range of chronic sinusitis on asthma was compared by Spearman correlation analysis. Results ① There was no statistical significance between the severity of nasal polyp and the degree of lung function limitation in asthmatic patients (P > 0.05), ② there was a positive correlation between the range of chronic sinusitis and the degree of lung function limitation in asthmatic patients (R =0.613, P < 0.05). ③ When chronic sinusitis complicated with sinosinusitis complex obstruction, nasal polyp group (r=0.408, P < 0.05) and simple sinusitis group (r=0.492, P < 0.05) could aggravate the degree of pulmonary function obstruction in asthma. Conclusion There is a certain positive correlation between the lesion scope and severity of chronic sinusitis and the highly restricted degree of pulmonary function in bronchial asthma, which needs to be further studied.
Key words： Chronic inusitis; Asthma; Nasalpolyposis; Severity; Critical Factor
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