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Open Access Article

International Medical Research Frontier. 2017; 1: (1) 4; - ; DOI: DOI:10.12208/j.imrf.20170004.

Clinical value of delayed percutaneous coronary intervention in patients with ST-elevation acute myocardial infarction
ST段抬高型急性心肌梗死患者延迟行经皮冠状动脉介入治疗的临床价值

作者: 丁鹏 *

西安医学院第二附属医院

*通讯作者: 丁鹏,单位:西安医学院第二附属医院;

发布时间: 2017-12-28 总浏览量: 2920

摘要

目的:探讨延迟行经皮冠状动脉介入治疗(PCI)在ST段抬高型急性心肌梗死(STEMI)治疗中的应用价值。方法:根据PCI治疗时机的不同将282例STEMI患者分为两组,观察组(202例)在发病后12~24h内行PCI,对照组(80例)在发病后6h内行溶栓治疗,后择期行PCI,对比两组的心功能及预后状况。结果:PCI治疗后,两组TIMI<2级的人数明显减少,TIMI2~3级的人数明显增多,且组间比较无显著性差异(P>0.05)。两组行PCI治疗3个月后,LVESVI、LVEDVI水平均明显降低,LEVF水平均明显升高,并且两组的LVESVI、LVEDVI、LEVF水平比较无显著差异(P>0.05)。 观察组的恶性心律失常、严重心衰发生率均显著高于对照组(P<0.05)。结论:对STEMI患者行延迟PCI可尽快疏通梗死相关动脉,改善心功能,减少心源性死亡。

关键词: 经皮冠状动脉介入治疗;ST段抬高型急性心肌梗死;溶栓

Abstract

[Abstract] Objective: To investigate the value of delayed percutaneous coronary intervention (PCI) in the treatment of ST-elevation acute myocardial infarction (STEMI).
Methods: 282 patients with STEMI were divided into two groups according to the duration of PCI. The observation group (n=202) used PCI within 12 to 24h after onset, and the control group (n=80) used thrombolytic therapy within 6h after onset, and then selected the date to use PCI. To compare the cardiac function and prognosis of two groups.
Results: After PCI, the number of patients with TIMI<2 of two groups were significantly reduced, and the number of patients with TIMI2 ~ 3 significantly were significantly increased, and there was no significant difference between the two groups (P>0.05). LVESVI and LVEDVI levels were significantly lower and LEVF levels were significantly higher of two groups after PCI 3 months . There was no significant difference in LVESVI, LVEDVI and LEVF between the two groups (P>0.05). The incidence of malignant arrhythmia and severe heart failure in the observation group were significantly higher than those in the control group (P<0.05).
Conclusion  : Delayed PCI in STEMI patients can unblock infarct-related arteries as soon as possible, and improve cardiac function and reduce cardiac death.

Key words: [Key words] Percutaneous coronary intervention; ST-segment elevation acute myocardial infarction; Thrombolysis

参考文献 References

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引用本文

丁鹏, ST段抬高型急性心肌梗死患者延迟行经皮冠状动脉介入治疗的临床价值[J]. 国际医药研究前沿, 2017; 1: (1) : -.