摘要
目的 讨论及研究多种西药联合使用的不良反应以及促进西药临床合理用药。方法 参与本次研究患者的数量为100例,时间为2025年1月份至2025年12月份,研究为期一年,随机数字表法分成对照组和实验组,每组50例患者,对照组常规的干预,实验组药学干预,对比两组患者临床疗效;不良反应发生率。结果 两组患者提供不同的干预策略后,实验组患者的治疗效果优于对照组,不良反应发生率低于对照组,p<0.05。结论 对于多种西药联合治疗的患者,提供药学干预,可以降低不良反应,提升治疗效果。
关键词: 多种西药;不良反应;西药临床合理用药
Abstract
Objective To investigate the adverse reactions associated with the combined use of multiple Western medications and to promote rational clinical medication practices. Methods A total of 100 patients were enrolled in this one-year study conducted from January to December 2025, randomly divided into a control group and an experimental group using a random number table, with 50 patients in each group. The control group received conventional interventions, while the experimental group received pharmaceutical interventions; clinical efficacy and adverse reaction rates were compared between the two groups. Results After implementing distinct intervention strategies, the experimental group demonstrated superior therapeutic outcomes and a lower incidence of adverse reactions compared to the control group (p <0.05). Conclusion Pharmaceutical interventions can reduce adverse reactions and enhance treatment efficacy in patients receiving combination therapy with multiple Western medications.
Key words: Various Western medicines; Adverse reactions; Rational clinical use of Western medicines
参考文献 References
[1] 于焕焕.多种西药联合使用的不良反应以及促进西药临床合理用药分析[J].中国科技期刊数据库 医药,2024(4): 0101-0104.
[2] 普布卓玛.多种西药合用的不良反应及促进西药临床合理用药的策略[J].中文科技期刊数据库(文摘版)医药卫生,2024(4):0088-0091.
[3] 马晶.探讨多种西药合用的不良反应及促进西药临床合理用药方案[J].中国科技期刊数据库 医药,2024(2):053-056.
[4] 赵俊.多种西药联合应用致不良反应与开展临床用药指导效果分析[J].临床合理用药,2024,17(2):156-158.
[5] 陈婷婷.头孢菌素类与多种西药联合使用所致的不良反应临床效果研究[J].中文科技期刊数据库(文摘版)医药卫生,2025(1):112-115.
[6] 宋彩瑜.多种西药合用不良反应及促进西药临床合理用药的探究[J].中国科技期刊数据库 医药,2023(9):067-070.
[7] 谢丽冰.探析多种西药合用的不良反应及促进西药临床合理用药的策略[J].中国科技期刊数据库医药, 2023(2):025-028.
[8] Stassen H H ,Bachmann S ,Bridler R , et al.Genetic predisposition to unwanted side effects under antidepressants and antipsychotics: a molecular-genetic study of 902 patients over 6 weeks[J].European Archives of Psychiatry and Clinical Neuroscience,2025,276(2):1-17.
[9] K T .Are topical non-steroidal anti-inflammatory drugs (NSAIDs) safer than oral NSAIDs? Or are the adverse effects of topical NSAIDs comparable to those of oral NSAIDs?[J].Osteoarthritis and cartilage,2021,29(11): 1624-1625.
[10] 戈秀萍.浅析多种西药合用不良反应与确保西药合理用药的对策[J].中国科技期刊数据库 医药,2023(6):5-8.