摘要
目的 评估牛黄解毒软胶囊与复方新诺明联合使用对急性扁桃体炎患者的临床疗效。方法 本研究共纳入60例急性扁桃体炎患者，分为两组，对照组和治疗组。两组患者在基线资料上无显著差异（P>0.05）。对照组仅接受复方新诺明治疗，而治疗组在此基础上加用了牛黄解毒软胶囊，治疗周期为5天。通过评估患者治疗前后的咽痛（或吞咽痛）、喉核红肿、咳嗽、发热、目赤、口干口臭和大便干燥等症状，来评价临床疗效。结果 治疗结束后，治疗组的临床有效率（96.7%）明显高于对照组（63.3%），经卡方检验分析，差异具有统计学意义（P<0.01）。治疗后，两组患者的各项症状均有所改善，这表明所用药物具有显著的临床疗效。而且，治疗组患者在改善上述症状方面明显优于对照组。结论 牛黄解毒软胶囊与复方新诺明联合治疗急性扁桃体炎展现出显著的疗效，是一种有效的临床治疗方案。
关键词： 牛黄解毒软胶囊；复方新诺明；急性扁桃体炎；临床有效
Abstract
Objective To evaluate the clinical efficacy of the combination of Niuhuang Jiedu soft capsules and compound sulfamethoxazole in the treatment of patients with acute tonsillitis. Methods A total of 60 patients with acute tonsillitis were included in this study and divided into two groups: the control group and the treatment group. There was no significant difference between the two groups in terms of baseline data (P>0.05). The control group only received compound sulfamethoxazole treatment, while the treatment group added Niuhuang Jiedu soft capsules on this basis, with a treatment period of 5 days. The clinical efficacy was evaluated by assessing the symptoms of sore throat (or pain swallowing), red and swollen laryngeal tonsils, cough, fever, red eyes, dry mouth and bad breath, and dry stool before and after treatment in patients. Results At the end of treatment, the clinical effective rate of the treatment group (96.7%) was significantly higher than that of the control group (63.3%), and the difference was statistically significant (P<0.01) after chi-square test analysis. After treatment, all symptoms in both groups improved, indicating that the drugs used had significant clinical efficacy. Moreover, the treatment group was significantly better than the control group in improving the above symptoms. Conclusion The combination of Niuhuang Jiedu soft capsules and compound sulfamethoxazole shows significant efficacy in the treatment of acute tonsillitis, and it is an effective clinical treatment plan.
Key words： Niuhuang Jiedu soft capsules; Compound Sulfamethoxazole; Acute Tonsillitis; Clinical Efficacy
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