Root cause analysis and treatment of cross matching incompatibility in blood transfusion department
输血科交叉配血不符病例的根因分析及处置措施

摘要

目的 分析输血科交叉配血不符病例原因和解决方法。方法 选择2021年2月-2022年2月接收的50例患者为研究对象，将其收集的血液由同一医生进行离心处理和检查，分析引起交叉配血不符的原因，并制定解决方法。结果 不规则抗体、自身抗体、高效价冷抗体、ABO亚型例数分别为21、2、16、11。不规则抗体、自身抗体、高效价冷抗体、ABO亚型抗体阳性率分别为42%、4%、32%、22%。不规则抗体阳性率明显高于其他三种类型（P<0.05）为差异显著，有统计学意义。结论 输血科交叉配血不符病例最大原因为不规则抗体。所以患者输血治疗时需要根据血液检查结果选择最合适的配血方法，保证患者输血安全，保证输血效果。

Abstract

Objective To analyze the causes and solutions of cross matching incompatibility in blood transfusion department.
Methods 50 patients received from February 2021 to February 2022 were selected as the research objects, and the blood collected by them was centrifuged and examined by the same doctor. The causes of cross matching incompatibility were analyzed, and solutions were formulated.
Results The number of irregular antibody, autoantibody, high titer cold antibody and ABO subtype were 21, 2, 16 and 11, respectively. The positive rates of irregular antibody, autoantibody, high titer cold antibody and ABO subtype antibody were 42%, 4%, 32% and 22% respectively. The positive rate of irregular antibody was significantly higher than that of the other three types (P<0.05).
Conclusion   Irregular antibody is the biggest cause of cross matching incompatibility in blood transfusion department. Therefore, patients need to choose the most appropriate blood matching method according to the blood test results to ensure the safety of blood transfusion and the effect of blood transfusion.