Clinical study on the combination of bromohexin and cefuroxime sodium in the treatment of pneumonia in children
溴己新与头孢呋辛钠联合治疗小儿肺炎临床研究

摘要

目的 探讨在小儿肺炎治疗中联用溴已新及头孢呋辛钠的意义。方法 试验者是2020.06至2022.07在医院治疗的肺炎患儿90例，以数字奇偶法分组，将45例接受头孢呋辛钠与维生素C治疗者视为对照组，另一组视为观察组，病例数共计45例，治疗方案为溴己新与头孢呋辛，比对疗效及安全性差异。结果 观察组用药总疗效率高于对照组，P＜0.05（χ2=6.154）；观察组咳嗽、肺部湿啰音及发热症状消失时间短于对照组，P＜0.05（t=11.555、5.818、8.328）；观察组用药不良反应率低于对照组，P＜0.05（χ2=4.939）。结论 以溴已新与头孢呋辛钠进行治疗，所得到的整体疗效更为理想，且安全性更高，建议推广。

Abstract

Objective: To explore the significance of combined use of bromohexin and cefuroxime sodium in the treatment of pneumonia in children.
Methods: the subjects were 90 children with pneumonia who were treated in the hospital from June 2020 to July 2022. They were grouped by digital parity method. 45 patients who received cefuroxime sodium and vitamin C treatment were regarded as the control group, and the other group was regarded as the observation group. The total number of cases was 45. The treatment scheme was bromohexin and cefuroxime. The efficacy and safety differences were compared.
Results: the total therapeutic efficiency of the observation group was higher than that of the control group (P < 0.05, ꭓ2 = 6.154); The disappearance time of cough, lung moist rale and fever in the observation group was shorter than that in the control group (P < 0.05) (t = 11.555, 5.818, 8.328); The adverse drug reaction rate of the observation group was lower than that of the control group (P < 0.05) (ꭓ2 = 4.939).
Conclusion  : the combination of bromohexin and cefuroxime sodium has better overall efficacy and higher safety. It is recommended to popularize it.