Clinical study of serum C-reactive protein, WBC and PCT in the diagnosis of fever in children
血清C-反应蛋白、WBC、PCT检验在小儿发热诊断中的临床研究

摘要

目的 疫分析血清C-反应蛋白、降钙素原（Procalcitonin，PCT）及血液白细胞（White Blood Cell，WBC）在小儿发热过程当中的变化，探究其临床诊断价值。方法 收集2022年1月至2022年4月我院儿科接诊的200例发热患儿作为研究对象，按感染类型将其分为细菌感染组（A组）和病毒感染组（B组），同时选择100例健康儿童作为对照。分析三组儿童在全血WBC、C-反应蛋白及血清PCT的差异。结果 A组患儿的WBC水平，C-反应蛋白以及血清PCT水平均显著高于B组和对照组（P< 0.05），而B组患儿这三个指标则与对照组相比没有显著差异（P> 0.05）。结论 在小儿发热的临床诊断过程当中，全血WBC、C-反应蛋白及血清PCT的检测具有极其重要的诊断价值。

Abstract

Objective: To analyze the changes of serum C-reactive protein (CRP), Procalcitonin (PCT) and White Blood Cell (WBC) in children with fever, and to explore their clinical diagnostic value.
Methods: A total of 200 children with fever admitted to our hospital from January 2022 to April 2022 were collected as the research objects. According to the infection type, they were divided into bacterial infection group (group A) and viral infection group (group B), and 100 healthy children were selected as the control group. The differences of whole blood WBC, C-reactive protein and serum PCT among the three groups were analyzed.
Results: The levels of WBC, C-reactive protein and serum PCT in group A were significantly higher than those in group B and control group (P< 0.05), but there was no significant difference in these three indexes between group B and control group (P> 0.05).
Conclusion  : The detection of whole blood WBC, C-reactive protein and serum PCT has very important diagnostic value in the clinical diagnosis of fever in children.