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Open Access Article

International Medical Research Frontier. 2022; 6: (4) ; 37-39 ; DOI: 10.12208/j.imrf.20220133.

Diagnostic value of mean reticulocyte hemoglobin (CHr) in iron deficiency anemia
网织红细胞平均血红蛋白量(CHr)对缺铁性贫血的诊断价值

作者: 张烨, 杨兰, 程少杰 *

联勤保障部队第九〇〇医院检验科 福建福州

*通讯作者: 程少杰,单位:联勤保障部队第九〇〇医院检验科 福建福州;

发布时间: 2022-09-14 总浏览量: 325

摘要

目的 探讨一种新型诊断缺铁性贫血(iron deficiency anemia,IDA)的方式,将网织红细胞平均血红蛋白量(reticulocyte hemoglobin content,CHr)作为主要诊断指标,观察具体诊断效能。方法 收集我院健康体检者和IDA患者标本各50例,标本均测定Hb、MCV、MCH、MCHC、CHr、SF并进行比较。采用西门子ADVIA2120i检测CHr,用电化学发光分析仪测量SF,借助ROC曲线对比CHr与SF诊断IDA的实际效果。结果 IDA患者Hb、MCV、MCH、MCHC、CHr、SF明显低于正常健康者,但CHr的灵敏度和特异度高于SF。结论 CHr在临床诊断IDA方面有一定的灵敏度和特异性,具有重要的临床价值。

关键词: 网织红细胞平均血红蛋白量;缺铁性贫血;铁蛋白

Abstract

Objective To explore a new diagnostic method for iron deficiency anemia (IDA), and to observe the specific diagnostic efficacy by using the mean reticulocyte hemoglobin content (CHr) as the main diagnostic index.
Methods 50 samples of healthy people and 50 samples of IDA patients in our hospital were collected. Hb, MCV, MCH, MCHC, Chr and SF were measured and compared. Siemens advia2120i was used to detect Chr, and electrochemiluminescence analyzer was used to measure SF. The actual effect of diagnosing IDA with Chr and SF was compared with ROC curve.
Results Hb, MCV, MCH, MCHC, Chr and SF of IDA patients were significantly lower than those of normal controls, but the sensitivity and specificity of Chr were higher than that of SF.
Conclusion   Chr has certain sensitivity and specificity in the clinical diagnosis of IDA and has important clinical value.

Key words: Average hemoglobin of reticulocyte; Iron-deficiency anemia; Ferritin

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引用本文

张烨, 杨兰, 程少杰, 网织红细胞平均血红蛋白量(CHr)对缺铁性贫血的诊断价值[J]. 国际医药研究前沿, 2022; 6: (4) : 37-39.